Department of Biochemistry

Biochemistry · GIMS

Integrated biochemistry education & diagnostic laboratory services

Supporting undergraduate and postgraduate training while providing reliable biochemical investigations to improve patient care and clinical decision-making.

Vision

To become a center of excellence in Diagnostics, impart top tier medical education and promote multi-disciplinary research for the benefit of community.

Mission

  • Enhancing patient care by increasing the scope of accredited tests with the use of updated technology.
  • Using innovative teaching learning tools for quality undergraduate and postgraduate teaching.
  • Collaborating for multidisciplinary research at departmental and institutional level.

Department Information

Sr. No. Heading Details
1 Name of the Department Biochemistry
2 Department Email biochemistrygims19@gmail.com
3 Date of Establishment 2017
4 Name of the first Head of Department Dr. Vanita Lal
5 Names of present Head of Department Dr. Manisha Singh
/

  • Training of faculty, staff and implementation of newly published 2023 version of ISO l15189 lab quality management guidelines.
  • Conducting ECHO sessions for awareness of medical community about pre analytical variables that are associated with various common biochemical parameters, training and sensitization of lab technician regarding importance of maintaining quality in the Lab.
  • Conducting studies using newer and innovative teaching techniques to enhance retention of subject among undergraduate medical students.
  • Organising guest lecture, Workshops and CME’S
  • Student workshops on basic molecular techniques
  • Starting Stone analysis centre in GIMS as gall stones and renal stones are very common in this belt.
  • Implement PG plan.

  • Increasing scope of parameters accredited by NABL. Target to bring all test parameters that we do, to come under NABL scope.
  • Apply for NIDAN grant to Start LCMS based diagnostic centre for Inborn Errors of Metabolism screening in association with department of paediatrics for GIMS.
  • Electrophoresis & Immunofixation for multiple Myeloma screening and diagnosis.
  • To start PhD
  • Centre of excellence in Diagnostic, Training & teaching.
  • Improving Laboratory infrastructure by including new high throughput analysers and providing exhaustive panel of tests for patient care as available in KGMU and SGPGI.

Test Facilities Available

Hormones & Special Tests Liver, Lipid & Enzymes Metabolic, Electrolytes & Markers
TSH
TT3
TT4
AFP
β-HCG
Ferritin
PSA
LH
FSH
Valproic Acid 		Total Bilirubin
Direct Bilirubin
Indirect Bilirubin
SGOT (AST)
SGPT (ALT)
ALP
Amylase
Lipase
Total Cholesterol
Triglycerides (TG)
HDL
Urea
Uric Acid
Creatinine
Total Protein
Albumin 		Plasma Glucose
HbA1c
Insulin
Sodium
Potassium
Calcium
Magnesium
CRP
LDH
RA Factor
Troponin I

  • MBBS course- CBME curriculum is followed as per NMC guidelines. It include Didactic lectures, SGT, SDL, ECE, DOAP, AETCOM

  • Courses conducted – MBBS, BSc Nursing, Paramedical

  • Nursing & paramedical Training

  • Block Training programme

  • Collaborating with other MRUs such as Maulana Azad medical college, Delhi for multicentric projects -2024.
  • Two ICMR STS projects got approval in 2022 and 2023 promoting research in MBBS undergraduate students.
  • Teaching of MBBS students including lectures, practical, small group teaching.
  • Running of central biochemistry lab and emergency lab 24/7 conforming to NABL standards, with highly trained technicians in hospital.
  • Department faculty member are actively participating in research projects related to clinical lab, basic sciences, and medical education.
  • Department faculty member are part of GIMS Scientific research committee and playing active role is taking ahead the research output of the institution.

Patients Workload 2025

Workload Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec
Total No. of Patients (OPD) 5425 5162 5776 6269 7161 6582 7440 7141 7171 4946 7874 7743
Total No. of Tests (OPD) 29240 27987 32765 35595 41231 36886 41113 37305 37195 25220 34777 41131
Total No. of Patients (IPD) 3682 3429 3979 3834 4039 3945 4275 4219 4648 3583 4124 4776
Total No. of Tests (IPD) 20425 19824 22062 20749 23507 22826 25968 26274 29753 23532 25465 28299

UG / PG Teaching Schedule

Department of Biochemistry – Weekly Academic Timetable

Day 8:30 – 9:30 9:30 – 10:30 10:30 – 11:30 11:30 – 12:30 Lunch 1:30 – 2:30 2:30 – 4:30
Monday Biochemistry Lecture Lab / Clinical Posting Lunch Break SDL
Tuesday SDL Lab / Clinical Posting Lunch Break Tutorial Biochemistry Practical
Wednesday Biochemistry Lecture Lab / Clinical Posting Lunch Break SDL Journal Club / Seminar
Thursday SDL Lab / Clinical Posting Lunch Break Biochemistry Lecture DOAP
Friday SDL SGT / ECE Lunch Break Case Presentation Biochemistry Practical
Saturday SDL Micro Teaching Biochemistry Seminar Lunch Break

PG Curriculum Activities

Teaching Method Frequency
Seminar Presentation Every Saturday
Clinical Case Discussion Every Thursday
Journal Club Every Tuesday
Microteaching Every Tuesday
Self Directed Learning (SDL) Every Friday
Thesis Review 1st Monday Every Month

Results – UG & PG

MBBS First Professional Examination Performance Analysis

Year Examination Distinction Passed Failed Pass %
2024 M.B.B.S First Professional Examination 15 101 - 100%
2023 M.B.B.S First Professional Examination 01 101 02 98.05%
M.B.B.S Supplementary Examination - 01 02 33.33%
2022 M.B.B.S First Professional Examination 03 94 02 97.91%
M.B.B.S Supplementary Examination - 01 01 50%
2021 M.B.B.S First Professional Examination - 94 05 94.94%
M.B.B.S Supplementary Examination - 04 01 80%
2020 M.B.B.S First Professional Examination - 99 Nil 100%
M.B.B.S Supplementary Examination - Nil 01 0%
2019 M.B.B.S First Professional Examination - 97 02 97.97%
M.B.B.S Supplementary Examination - 02 01 66.66%
Research Projects – Department of Biochemistry

Research Projects – Department of Biochemistry

Intramural · Extramural · ICMR · WHO · Others  |  Ongoing & Completed

Research Projects by Faculty — ICMR, CST-UP & Intramural Grants ⌃
S.No Title of Research Project Principal / Guide Investigator Funding Agency / Nature Year Status
1 To develop miRNA based panel for early diagnosis of diabetic nephropathy PI – Dr. Devesh Intramural 2025 Ongoing
2 Synergistic Anticancer Potential of Thymoquinone Nanoparticles with Docetaxel in Prostate Cancer Cells PI – Utkarsh Singh Intramural 2025 Ongoing
3 Evaluating the association between thioredoxin interacting protein – nod like receptor family pyrin domain containing 3 inflammasome axis and nephropathy in type 2 diabetes mellitus patients Dr. Smriti Intramural 2025 Ongoing
4 Evaluation of sirt1 and sirt4 gene expression in circulating leukocytes in type 2 diabetes mellitus in western Uttar Pradesh Dr. Iram Intramural 2025 Ongoing
5 Evaluate the role of glycated fibrinogen as a biomarker in coronary artery disease (CAD) among patients aged 18–75 years in tertiary care hospital of western Uttar Pradesh Dr. Aaliya Intramural 2025 Ongoing
6 Enhancing Patient-Centered Care: Implementation and Evaluation of a Mobile-Based Patient Care and Information System with Chatbot Interaction. UP-CST PI – Dr. Manisha Singh Extramural – CST-UP 2024 Ongoing
7 Investigating the influence of clinico-socio-demographic factors on ocular disorders in diabetes mellitus: A study from western Uttar Pradesh India Guide – Dr. Manisha Singh Extramural – ICMR-STS 2024 Completed & Published
8 Study of serum uric acid levels with the severity in COVID Disease PI – Dr. Mamta Padhy
Co-PI – Dr. Manisha Singh
Co-PI – Dr. Devesh Sharma		 Intramural 2023 Completed & Published
9 Implementation of Flipped Classroom Model in teaching Biochemistry to Phase-I MBBS Students PI – Dr. Manisha Singh
Co-PI – Dr. Mamta Padhy		 Intramural 2022 Completed & Published
10 Maternal circulatory levels of procalcitonin, uric acid, and lipid profile in Early-onset preeclampsia and Late-onset preeclampsia Co-Guide – Dr. Manisha Singh Intramural 2022 Completed & Published
11 Implementation of 5S management method for lean healthcare in clinical biochemistry laboratory of a government hospital in India — International Journal of Health Sciences PI – Dr. Manisha Singh
Co-PI – Dr. Mamta Padhy		 Intramural 2022 Completed & Published
12 The Effect of Self-Care Training using E-Learning and Teach-Back Methods for Pregnant Patients undergoing OGTT test PI – Dr. Manisha Singh Intramural – ICMR-STS — Completed & Published
Research Projects by the Department of Biochemistry — Topic Listing ⌃
  • To study the predictors of disease severity in COVID 19 infected patients in a tertiary care center in Greater Noida.
  • Role of short term oral estradiol in natural estrogen deficient symptomatic COVID 19 patients – a RCT.
  • COVID 19 infection in pregnancy analysis of potential feto maternal effects and risk of vertical transmission.
  • Evaluation of laboratory parameter for diagnostic accuracy in RTPCR positive COVID 19 patients.
  • To explore any association of vitamin D3 with laboratory parameter in COVID 19 patients preeclampsia.
  • Relationship between Telomere length, inflammatory markers, Endothelin-1 and oxidative stress in preeclampsia.
  • Implementation of Flipped Classroom Model in teaching Biochemistry to Phase – I MBBS students.
  • Implementation of 5S management method for lean health care in clinical biochemistry laboratory of a government hospital in Uttar Pradesh, India.
Research Projects Undertaken by Faculty — Detailed Record ⌃
S.No Title of Research Project Principal Investigator Co-Investigators Nature of Study Year Status
1 Correlation of Vitamin D Levels with Glycemic Control in Type-2 Diabetes Mellitus Patients Dr. Manisha Singh Dr. Mamta Padhy, Dr. Devesh Sharma Clinical Study 2025 Ongoing
2 Assessment of Teaching-Learning Methods in Biochemistry among Phase-I MBBS Students Dr. Manisha Singh Department Faculty Medical Education Research 2025 Ongoing
3 Application of Six Sigma Metrics in Quality Control of Clinical Biochemistry Laboratory Dr. Ijen Bhattacharya Dr. Manisha Singh Laboratory Research 2024 Completed
4 Quality Assurance and Laboratory Accreditation Preparedness in Clinical Biochemistry Laboratory Dr. Ijen Bhattacharya Dr. Devesh Sharma Laboratory Audit Study 2024 Ongoing
5 Serum Uric Acid as Predictor of Acute Kidney Injury in COVID-19 Patients Dr. Mamta Padhy Dr. Manisha Singh Clinical Research 2023 Completed
6 Biochemical Parameters in Metabolic Syndrome among Adult Population Dr. Manisha Singh Dr. Ijen Bhattacharya Community Based Study 2023 Completed
7 Lipid Profile Alterations and Cardiovascular Risk Markers in Hypertensive Patients Dr. Devesh Sharma Dr. Mamta Padhy Clinical Study 2022 Completed
8 Evaluation of Biochemical Markers in Preeclampsia and Pregnancy-Induced Hypertension Dr. Mamta Padhy Dr. Manisha Singh Hospital-Based Study 2021 Completed

  • Develop the department as a Centre of excellence for undergraduate & postgraduate training.

  • To provide state of art diagnostic facility in Gautham Buddha Nagar.

  • To improvise the research in the department.

CMEs / Workshops / Academic Activities

Department Continuous Medical Education & Faculty Development Activities

Year S.No CME / Workshop Venue / Organizer Role
2025 1 CME-cum Hands-on Workshop on Protein Electrophoresis GIMS, Greater Noida (July 2025) Organized / Attended
2 Workshop on Patient Safety Officer GIMS Organized / Attended
3 Hands-on Workshop & CME on Clinical Application of RT-PCR GIMS Attended
4 Hands-on Workshop on Next Generation Sequencing (NGS) DHR / GIMS Attended
5 DHR Manuscript Writing Workshop GIMS MRU Attended
6 DHR Master Class on Sample Size Calculation ICMR Attended
7 CME: Chasing Targets – Lipid Goals and Beyond PGICH, Noida Attended
8 Basic Course in Medical Education Workshop GIMS Resource Person / Attended
9 Certified Professional for Quality Implementation in Hospitals GIMS Attended
2024 10 ISO 15189:2022 & Internal Auditor Workshop GIMS Attended
11 Hands-on Workshop on Pipette Calibration GIMS Attended
12 Multi-Omics in Precision Diagnostics (14 days) ICMR-NICPR Attended
13 Workshop on Cell Culture (3 days) HIMSAR, New Delhi Attended
14 BCME Workshop (3 days) GIMS Attended
15 International Webinar on Human Factors in Healthcare Online Attended
16 Workshop on Medication Management & Safety GIMS Attended
2023 17 Hands-on Workshop on Droplet Digital PCR GIMS (Sep 2023) Organized / Attended
18 SARS-CoV-2 Genome Sequencing Workshop NICPR Attended
19 CME on Lipid Profile & Cardiovascular Risk GIMS Attended
20 Workshop on Capillary Electrophoresis & HPLC MAMC Attended
21 Research Grant Writing Workshop GIMS Attended
2022 22 NABL Training Program (4 days) MELAP & GIMS (Nov 2022) Organized / Attended
23 Basic Molecular Diagnostics Workshop GIMS Attended
24 5th India ddPCR Symposium National Attended
25 CME on Pharmacovigilance GIMS Attended
2021 26 CME on COVID-19 Preparedness GIMS (30 Oct 2021) Attended
27 CME on CSSD & Infection Control GIMS (14 Sept 2021) Attended
28 Webinar on COVID-19 Biochemistry Online (26 Feb 2021) Attended
29 Six Sigma in Clinical Laboratory Webinar Online (5 Feb 2021) Attended
30 CME on Hemovigilance GIMS (6 Apr 2021) Attended
31 ACBICON 2021 (Hybrid) National Attended

  • Conducted ISO-15189 and Internal Auditor WORKSHOP-2022

  • HANDS ON WORKSHOP ON PIPETTE CALIBRATION

  • Guest lectures
    1. Guest Lecture on Cell Culture
    2. Guest Lecture on Integration of Metabolism
    3. Guest Lecture on Role of Bioinformatics in Public Health
    4. Constitution Day Celebration | 26th Nov’2024 Department of Biochemistry

  • Pipette calibration workshop conducted by biochemistry department on 27th July.

  • A CME cum Workshop was organized on Advanced Molecular Techniques in Medical Diagnostics on 22nd & 23rd April 2019. This event had been conceived with the idea of providing platform for amalgamation of modern technologies in diagnosis of different disorders. The CME cum Workshop offered a wonderful mix of high caliber plenary speakers, an engaging scientific program and interesting talks on “Advanced molecular techniques in medical diagnostics”.

  • NABL training program was conducted for 2 days on 11th and 12th December 2019.

  • Conducted guest lecture on “Cell Culture in Medical Research- current trends and future perspectives”, given by Prof B C Koner, HOD, Dept. of Biochemistry, MAMC, New Delhi.

  • Guest lecture on “Pivotal role of cell culture in Research by Dr Rajarshi Kar

  • Implementation of 5S management method for lean health care in clinical biochemistry laboratory of a government hospital in Uttar Pradesh, India

  • Implementation of Flipped Classroom Model in teaching Biochemistry to Phase – I MBBS students.

  • Relationship between Telomere length, inflammatory markers, Endothelin- 1 and oxidative stress in preeclampsia

  • To explore any association of vitamin D3 with laboratory parameter in COVID 19 patients preeclampsia

  • Evaluation of laboratory parameter for diagnostic accuracy in RTPCR positive COVID 19 patients

  • COVID 19 infection in pregnancy analysis of potential feto maternal effects and risk of vertical transmission.

  • Role of short term oral estradiol in natural estrogen deficient symptomatic COVID 19 patients- a RCT.

  • To study the predictors of disease severity in COVID 19 infected patients in a tertiary care center in Greater Noida.

Faculty Publications (Last 5 Years)

Department of Biochemistry — Research & Scientific Contributions

Dr. Manisha Singh
Professor & Head
Department Faculty
Publications: 17
  • Agarwal R, Singh U, Bhandari B & Singh M (2025). Effects of yoga on epigenetics and gene expression: Emerging evidence. Indian Journal of Physiology and Allied Sciences.
  • Singh M et al (2025). Implementing Quiz Game As A Learning Tool in Biochemistry for Phase I Medical Students. International Journal of Pharmaceutical Quality Assurance.
  • Tomar US et al (2024). Comparative Analysis of Tech back, E-Learning Videos and Traditional Methods in Communicating OGTT Guidelines. African Journal of Biological Sciences.
  • Singh S et al (2024). Application of Six Sigma metrics for assessing the quality management of biochemical analytes. Asian Journal of Medical Sciences.
  • Tomar US et al (2024). Vitamin D: A Comprehensive Review. Journal of Academy of Biomedical Sciences.
  • Sinha A et al (2024). Clinico-socio-demographic factors and ocular disorders in diabetes mellitus. Indian Journal of Clinical and Experimental Ophthalmology.
  • Padhy M et al (2023). Serum uric acid levels with severity of kidney injury in COVID. IJCPRR.
  • Tripathi P et al (2023). Small Dense LDL as a biomarker for cardiovascular diseases. IOSR-JDMS.
  • Ravoori SR et al (2022). Endothelin-1, antioxidants and inflammatory markers in preeclampsia. Journal of Clinical and Diagnostic Research.
  • Rao RS et al (2022). Telomere length and oxidative stress markers in preeclampsia. Journal of Pharmaceutical Negative Results.
  • Rao RS et al (2022). Maternal endothelin-1 and MMP-9 gene expression in preeclampsia. Journal of Obstetrics and Gynecology of India.
  • Singh M et al (2022). Implementation of 5S management method for lean healthcare in clinical biochemistry lab. International Journal of Health Sciences.
  • Rao RS et al (2022). Procalcitonin, uric acid and lipid profile in early vs late preeclampsia. International Journal of Health Sciences.
  • Singh M et al (2022). Flipped Classroom Model in teaching Biochemistry to Phase-I MBBS Students. EJMCM.
  • Padhy M et al (2021). Vitamin D3 correlation with laboratory parameters in COVID-19 patients. IJHCR.
  • Seth S et al (2021). Estradiol supplementation in symptomatic postmenopausal COVID-19 females. J Mid-life Health.
  • Padhy M et al (2021). Diagnostic accuracy of laboratory parameters in COVID-19 patients. IJHCR.
Dr. Ijen Bhattacharya
Professor
Department Faculty
Publications: 5
  • Singh M et al (2025). Quiz Game learning tool in Biochemistry teaching. IJPQA.
  • Sahu S et al (2025). Recent Advances in Mammography. Journal of Indian University.
  • Tomar US et al (2024). OGTT patient communication methods comparison. African Journal of Biological Sciences.
  • Singh S et al (2024). Six Sigma metrics in clinical laboratory quality management. Asian Journal of Medical Sciences.
  • Kumar A et al (2020). Vitamin B12, Folate and Ferritin levels in hypothyroidism patients. IJMRP.
Dr. Mamta Padhy
Associate Professor
Department Faculty
Publications: 15
  • Gupta RK et al (2025). Clinico-laboratory profile of SARS-CoV-2 induced MIS-C: multicentric cohort study. Medical Journal Armed Forces India.
  • Singh M et al (2025). Quiz Game learning tool in Biochemistry teaching. IJPQA.
  • Tomar US et al (2024). Communication of OGTT guidelines to pregnant patients. African Journal of Biological Sciences.
  • Singh S et al (2024). Six Sigma metrics for quality management of biochemical analytes. Asian Journal of Medical Sciences.
  • Gupta S et al (2023). Vitamin D level association with lipid profile in Type-2 Diabetes Mellitus. European Journal of Cardiovascular Medicine.
  • Padhy M et al (2023). Serum uric acid levels with severity of kidney injury in COVID. IJCPRR.
  • Tripathi P et al (2023). Small Dense LDL as cardiovascular biomarker. IOSR-JDMS.
  • Rao RS et al (2022). Telomere length and oxidative stress markers in preeclampsia. Journal of Pharmaceutical Negative Results.
  • Rao RS et al (2022). Maternal endothelin-1 and MMP-9 gene expression in preeclampsia. Journal of Obstetrics and Gynecology of India.
  • Singh M et al (2022). 5S management method for lean healthcare in clinical biochemistry lab. International Journal of Health Sciences.
  • Rao RS et al (2022). Procalcitonin, uric acid and lipid profile in early vs late preeclampsia. International Journal of Health Sciences.
  • Singh M et al (2022). Flipped classroom teaching model in Biochemistry. EJMCM.
  • Gupta AK et al (2021). Long COVID: pattern of persistent symptoms. Trends in Medical Research.
  • Padhy M et al (2021). Vitamin D3 correlation with laboratory parameters in COVID-19. IJHCR.
  • Padhy M et al (2021). Diagnostic accuracy of laboratory parameters in COVID-19 patients. IJHCR.
Dr. Devesh Sharma
Assistant Professor
Department Faculty
Publications: 10
  • Patnaik A & Sharma D (2025). Cognitive Framework for the Study of the Senses. MetaScientia.
  • Garg S, Sharma D et al (2025). Pre-Test preparation of patients for plasma glucose estimation. Annals of Pathology and Laboratory Medicine.
  • Singh M et al (2025). Quiz Game learning tool in Biochemistry teaching. IJPQA.
  • Tomar US et al (2024). OGTT patient communication methods comparison. African Journal of Biological Sciences.
  • Singh S et al (2024). Six Sigma metrics in clinical laboratory quality management. Asian Journal of Medical Sciences.
  • Padhy M et al (2023). Serum uric acid levels and kidney injury severity in COVID. IJCPRR.
  • Tripathi P et al (2023). Small Dense LDL biomarker for cardiovascular diseases. IOSR-JDMS.
  • Grover S et al (2023). Cognitive function and Vitamin D binding protein levels in COPD. Int J Non-Commun Dis.
  • Sharma D & Vinocha A (2020). Benign ovarian cysts with raised CA-125 levels. Journal of Laboratory Physicians.
  • Sharma D et al (2020). Laboratory changes in SARS-CoV-2 infection: a review. Indian Journal of Medical Biochemistry.

VISION PLAN - DEPARTMENT OF BIOCHEMISTRY

Present Status Next 1 Year Next 5 Years Next 10 Years
MBBS Teaching. To implement PG Plan Upgrading Research Centre of excellence in Diagnostic, Training & teaching.
Diagnostic Laboratory. Training of all staff members according to NABL standards. Screening of Inborn Errors of Metabolism.
To facilitate research and get extramural projects sanctioned Electrophoresis & Immunofixation for multiple Myeloma.
Organising CMEs & Workshops To start PhD
Department of Biochemistry

Department Gallery